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Additionally, I don't rest to restore mana and HP -- I think that operating with full HP and mana all the time makes it too easy, especially once you have rune of return. I don't "wait around" to restore HP either, but I do allow myself to take advantage of low HP situations to play with Wand of Create Traps or to walk back to town and sell items.
Oh, I do allow myself to rest for a few seconds near the top of the hour if a monster is active to wake me -- this lets me get 2 points of mana regen instead of 1. I don't think that's much of a cheat, especially since most of the time I forget to do it.
After a bunch of frustrating Part 2 deaths, I finally won the whole thing on Easy difficulty. I tried ExpertsOnly next and got destroyed.. that might be actually impossible under the rules I set for myself.